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Research:
Genetical genomics in Caenorhabditis elegans
Natural variation in transcript abundance can be found in many organisms, including Caenorhabditis elegans (C.elegans). These variations in transcript abundance might cause the variation in phenotypes observed between the individuals of a C.elegans recombinant inbred line (RIL) population. Through genetical genomics, quantitative trait loci (QTL) mapping of transcript abundance, the regulatory loci for many genes can be uncovered. By combining these loci putative transcript regulation networks can be constructed. In this way the underlying mechanisms of traits for which natural variation has been found can be unraveled.
>> Publications by Basten Snoek
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