Kammenga, J.E. (Jan)

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Dr.ir. J.E. Kammenga
Associate Professor
Molecular Ecology

 

email:     Jan.Kammenga@wur.nl 
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C. elegans
Picture: Agnieszka Doroszuk

Research:

We use quantitative genetic approaches (QTL studies) to map complex traits and to study QTL-environment interactions. To identify candidate genes underlying complex traits we perform mutation analysis and complementation studies.

We study gene-environment interactions in C. elegans both at the single gene as well as whole genome level. We have developed an immortal population of nearly 1200 recombinant inbred lines obtained from a cross betwen Bristol N2 and CB4856 which we use for mapping complex traits.

At the genome level we collaborate with the group of Ritsert Jansen to study gene-environment interactions. Here we focus on the genetic variation of gene expression (genetical genomics) using a mapping population obtained from a cross betwen Bristol N2 and CB4856.

We further collaborate with Mike Herman focusing on gene-environment interactions in natural populations of C. elegans.
 

Research group:  


»         Publications by Jan Kammenga

Recent publications:

 


Projects:

  • » GRAPPLE 
    Iterative modelling of gene regulatory interactions underlying stress, disease and ageing in C. elegans
  • » PANACEA 
    Quantitative pathway analysis of natural variation in complex disease signaling in C. elegans  
  • » NEMADAPT
    Molecular architecture of environmental adaptation in natural populations of the nematode Caenorhabditis elegans 

Teaching subjects:


BSc thesis topics:


MSc thesis subjects:

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